2024

Bakhsh A, Gillespie CS, Richardson GE, Mustafa MA, Millward CP, Mirza N, Jenkinson MD. Evaluation of systemic inflammation in seizure phenotypes following meningioma resection. J Clin Neurosci. 2024 Feb;120:82-86. doi: 10.1016/j.jocn.2024.01.003. Epub 2024 Jan 13. PMID: 38219304.

Khan ZR, Welsby PJ, Stasik I, Hayes JM. “Discovery of potent multikinase type-II inhibitors targeting CDK5 in the DFG-out inactive state with promising potential against glioblastoma” Med. Chem. 2024, 67, 7539.

Chen J, Laverty DJ, Talele S, Bale A, Carlson BL, Porath KA, Bakken KK, Burgenske DM, Decker PA, Vaubel RA, Eckel-Passow JE, Bhargava R, Lou Z, Hamerlik P, Harley B, Elmquist WF, Nagel ZD, Gupta SK, Sarkaria JN. Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization. Sci Transl Med. 2024 Feb 14;16(734):eadj5962. doi: 10.1126/scitranslmed.adj5962. Epub 2024 Feb 14. PMID: 38354228; PMCID: PMC11064970.

Dobeson CB, Baxter M, Rowe M, Kingdon S, Park S, Bond H, Taylor K, Islim AI, King J, Millward CP, Zakaria R, Clynch AL, Keshwara SM, Eltinay A, Kviat L, Robinson R, Haris PA, Samuel R, Venkatesh V, Derby S, Ahmad S, Smith F, Robinson S, Kathirgamakarthigeyan S, Narramneni LR, Hannan CJ, Lewis J; National Oncology Trainees' Collaborative for Healthcare Research (NOTCH). Management Approaches in WHO Grade III Meningioma: A National Oncology Trainees' Collaborative for Healthcare Research (NOTCH) UK Multi-Centre Retrospective Study. Clin Oncol (R Coll Radiol). 2024 May 13:S0936-6555(24)00181-X. doi: 10.1016/j.clon.2024.05.006. Epub ahead of print. PMID: 38849235.

Donofrio CA, Bertazzoni G, Riccio L, Pinacoli A, Pianta L, Generali D, Ungari M, Servadei F, Roncaroli F, Fioravanti A. Intrasellar Dermoid Cyst: Case Report of a Rare Lesion and Systematic Literature Review Comparing Intrasellar, Suprasellar, and Parasellar Locations. World Neurosurg. 2024 Feb;182:83-90. doi: 10.1016/j.wneu.2023.11.057. Epub 2023 Nov 22. PMID: 37995988.

Gilbertson RJ, Behjati S, Böttcher AL, Bronner ME, Burridge M, Clausing H, Clifford H, Danaher T, Donovan LK, Drost J, Eggermont AMM, Emerson C, Flores MG, Hamerlik P, Jabado N, Jones A, Kaessmann H, Kleinman CL, Kool M, Kutscher LM, Lindberg G, Linnane E, Marioni JC, Maris JM, Monje M, Macaskill A, Niederer S, Northcott PA, Peeters E, Plieger-van Solkema W, Preußner L, Rios AC, Rippe K, Sandford P, Sgourakis NG, Shlien A, Smith P, Straathof K, Sullivan PJ, Suvà ML, Taylor MD, Thompson E, Vento-Tormo R, Wainwright BJ, Wechsler-Reya RJ, Westermann F, Winslade S, Al-Lazikani B, Pfister SM. The Virtual Child. Cancer Discov. 2024 Apr 4;14(4):663-668. doi: 10.1158/2159-8290.CD-23-1500. PMID: 38571421.

Purshouse K, Bulbeck HJ, Rooney AG, Noble KE, Carruthers RD, Thompson G, Hamerlik P, Yap C, Kurian KM, Jefferies SJ, Lopez JS, Jenkinson MD, Hanemann CO, Stead LF. Adult brain tumour research in 2024: Status, challenges and recommendations. Neuropathol Appl Neurobiol. 2024 Apr;50(2):e12979. doi: 10.1111/nan.12979. PMID: 38605644.

Rahman R, Shi DD, Reitman ZJ, Hamerlik P, de Groot JF, Haas-Kogan DA, D'Andrea AD, Sulman EP, Tanner K, Agar NYR, Sarkaria JN, Tinkle CL, Bindra RS, Mehta MP, Wen PY. DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology. Neuro Oncol. 2024 Mar 22:noae072. doi: 10.1093/neuonc/noae072. Epub ahead of print. PMID: 38770568.

Richardson GE, Clynch AL, Mustafa MA, Gillespie CS, Chawira A, Walkden J, Brodbelt AR, Chavredakis E, McMahon CJ, Mills SJ, Islim AI, Mallucci CL, Jenkinson MD. Tectal Plate Glioma: A Clinical and Radiological Analysis of Progression and Management in Adults. World Neurosurg. 2024 Jan 27:S1878-8750(24)00119-0. 

Staniszewska AD, Pilger D, Gill SJ, Jamal K, Bohin N, Guzzetti S, Gordon J, Hamm G, Mundin G, Illuzzi G, Pike A, McWilliams L, Maglennon G, Rose J, Hawthorne G, Cortes Gonzalez M, Halldin C, Johnström P, Schou M, Critchlow SE, Fawell S, Johannes JW, Leo E, Davies BR, Cosulich S, Sarkaria JN, O'Connor MJ, Hamerlik P. Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1. Clin Cancer Res. 2024 Apr 1;30(7):1338-1351. doi: 10.1158/1078-0432.CCR-23-2094. PMID: 37967136.

Suppree JS, Kannan S, Hughes DM, Jenkinson MD, Zakaria R. Letter: Estimating the baseline local recurrence rate for a brain metastasis after neurosurgical resection. Clin Exp Metastasis. 2024 Apr;41(2):155-157. doi: 10.1007/s10585-024-10274-6. Epub 2024 Feb 14. PMID: 38353933.

Tanner G, Barrow R, Ajaib S, Al-Jabri M, Ahmed N, Pollock S, Finetti M, Rippaus N, Bruns AF, Syed K, Poulter JA, Matthews L, Hughes T, Wilson E, Johnson C, Varn FS, Brüning-Richardson A, Hogg C, Droop A, Gusnanto A, Care MA, Cutillo L, Westhead DR, Short SC, Jenkinson MD, Brodbelt A, Chakrabarty A, Ismail A, Verhaak RGW, Stead LF. IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy. Genome Biol. 2024 Feb 7;25(1):45. doi: 10.1186/s13059-024-03172-3. PMID: 38326875; PMCID: PMC10848526.

2023

Abdelmohsen HAM, Copeland NA, Hardy JG. Light-responsive biomaterials for ocular drug delivery. Drug Deliv Transl Res. 2023 Aug;13(8):2159-2182.

Mathomes RT, Koulas SM, Tsialtas I, Stravodimos G., Welsby PJ, Psarra AMG, Stasik I, Leonidas DD*, Hayes JM*. “Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its’ potential against glioblastoma in cellular models”, Chemico-Biological Interactions 2023, 382, 110568.

Emmerich TD, Hayes JM*, “In Silico-Motivated Discovery of Novel Potent Glycogen Synthase-3 Inhibitors: 1-(Alkyl/arylamino)-3H-naphtho[1,2,3-de]quinoline-2,7-dione Identified as a Scaffold for Kinase Inhibitor Development”, Pharmaceuticals 2023, 16, 661.

Ajaib S, Lodha D, Pollock S, Hemmings G, Finetti MA, Gusnanto A, Chakrabarty A, Ismail A, Wilson E, Varn FS, Hunter B, Filby A, Brockman AA, McDonald D, Verhaak RGW, Ihrie RA, Stead LF. GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data. Neuro Oncol. 2023 Jul 6;25(7):1236-1248. doi: 10.1093/neuonc/noad021. PMID: 36689332; PMCID: PMC10326489.

Ali AMS, Varasteh AA, Konteas AB, Doherty JA, Iqbal N, Vupputuri H, Brodbelt AR. When is a staging scan required for newly diagnosed brain lesions on CT? A multivariate logistic regression analysis. Acta Neurochir (Wien). 2023 Apr;165(4):1065-1073. doi: 10.1007/s00701-022-05374-9. Epub 2022 Oct 8. PMID: 36208346.

Armeni E, Alexandraki KI, Roncaroli F, Grossman AB. Primary Pituitary Carcinoids Do Not Exist: A Reappraisal in the Era of Pituitary Neuroendocrine Tumours. Arch Med Res. 2023 Dec;54(8):102841. doi: 10.1016/j.arcmed.2023.102841. Epub 2023 Jun 30. PMID: 37394342.

Baldwin L, Jones EJ, Iles A, Carding SR, Pamme N, Dyer CE, Greenman J. Development of a dual-flow tissue perfusion device for modeling the gastrointestinal tract-brain axis. Biomicrofluidics. 2023 Oct 11;17(5):054104. doi: 10.1063/5.0168953. PMID: 37840538; PMCID: PMC10569815.

Barry A, Samuel SF, Hosni I, Moursi A, Feugere L, Sennett CJ, Deepak S, Achawal S, Rajaraman C, Iles A, Wollenberg Valero KC, Scott IS, Green V, Stead LF, Greenman J, Wade MA, Beltran-Alvarez P. Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system. Lab Chip. 2023 May 30;23(11):2664-2682. doi: 10.1039/d3lc00204g. PMID: 37191188.

Bjørknes B, Neye OE, Hamerlik P, Jauffred L. Immunostaining protocol for infiltrating brain cancer spheroids for light-sheet imaging. PLoS One. 2023 Feb 9;18(2):e0281161. 

Burrows L, Patel J, Islim AI, Jenkinson MD, Mills SJ, Chen K. A semi-automatic segmentation method for meningioma developed using a variational approach model. Neuroradiol J. 2023 Dec 26:19714009231224442. 

Clynch AL, Gillespie CS, Richardson GE, Mustafa MA, Islim AI, Keshwara SM Bakhsh A, Kumar S, Zakaria R, Millward CP, Mills SJ, Brodbelt AR, Jenkinson MD. Tranexamic acid use in meningioma surgery - A systematic review and meta-analysis. J Clin Neurosci. 2023 Apr; 110:53-60. 

Clynch AL, Norrington M, Mustafa MA, Richardson GE, Doherty JA, Humphries TJ Gillespie CS, Keshwara SM, McMahon CJ, Islim AI, Jenkinson MD, P Millward C, Brodbelt AR. Cranial meningioma with bone involvement: surgical strategies and clinical considerations. Acta Neurochir (Wien). 2023 May;165(5):1355-1363. 

Donofrio CA, PizzimenU C, Djoukhadar I, Kearney T, Gnanalingham K, Roncaroli F. Colorectal carcinoma to pituitary tumour: tumour to tumour metastasis. Br J Neurosurg. 2023 Oct;37(5):1367-1370. 

Garcia-Diaz C, PöysU A, Mereu E, Clements MP, Brooks LJ, Galvez-Cancino F, CasUllo SP, Tang W, Beabe G, Courtot L, Ruiz S, Roncaroli F, Yuan Y, Marguerat S, Quezada SA, Heyn H, Parrinello S. Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin. Cell Rep. 2023 May 30;42(5):112472. 

Gillespie CS, Mustafa MA, Richardson GE, Alam AM, Lee KS, Hughes DM, Escriu C, Zakaria R. Genomic Alterations and the Incidence of Brain Metastases in Advanced and Metastatic NSCLC: A Systematic Review and Meta-Analysis. J Thorac Oncol. 2023 Dec;18(12):1703-1713.

Gillespie CS, Richardson GE, Mustafa MA, Taweel BA, Bakhsh A, Kumar S Keshwara SM, Islim AI, Mehta S, Millward CP, Brodbelt AR, Mills SJ, Jenkinson.MD. Volumetric Growth and Growth Curve Analysis of Residual Intracranial Meningioma. Neurosurgery. 2023 Apr 1;92(4):734-744. 

Gregory GE, Islim AI, Hannan CJ, Jones AP, Hammerbeck-Ward C, Rutherford SA Freeman SR, Lloyd S, Kalamarides M, Smith MJ, Couper K, McBain CA, Jenkinson MD Brough D, King AT, Evans DG, Pathmanaban ON. The clinical, genetic, and immune landscape of meningioma in patients with NF2-schwannomatosis. Neurooncol Adv..2023 Jun 3;5(Suppl 1):i94-i104. 

Islim AI, Lee JX, Mustafa MA, Millward CP, Gillespie CS, Richardson GE Taweel BA, Chavredakis E, Mills SJ, Brodbelt AR, Jenkinson MD. Sporadic multiple intracranial meningioma does not infer worse patient outcomes: results from a case control study. J Neuro-oncol. 2023 Jan;161(2):287-295. 

Islim AI, Millward CP, Mills SJ, Fountain DM, Zakaria R, Pathmanaban ON Mathew RK, Santarius T, Jenkinson MD. The management of incidental meningioma: An unresolved clinical conundrum. Neurooncol Adv. 2023 Jun 3;5(Suppl 1):i26-i34. 

Keck MK, Sill M, Wittmann A, Joshi P, Stichel D, Beck P, Okonechnikow K, Sievers P, Wefers AK, Roncaroli F, Avula S, McCabe MG, Hayden JT, Wesseling P, Øra I, Nistér M, Kranendonk MEG, Tops BBJ, Zapotocky M, Zamecnik J, Vasiljevic A, Fenouil T, Meyronet D, von Hoff K, Schüller U, Loiseau H, Figarella-Branger D, Kramm CM, Sturm D, Scheie D, Rauramaa T, Pesola J, Gojo J, Haberler C, Brandner S, Jacques T, Sexton Oates A, Saffery R, Koscielniak E, Baker SJ, Yip S, Snuderl M, Ud Din N, Samuel D, Schramm K, Blattner-Johnson M, Selt F, Ecker J, Milde T, von Deimling A, Korshunov A, Perry A, Pfister SM, Sahm F, Solomon DA, Jones DTW. Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification. Acta Neuropathol. 2023 Jan;145(1):49-69. doi: 10.1007/s00401-022-02516-2. Epub 2022 Nov 27. Erratum in: Acta Neuropathol. 2023 Apr;145(4):511-514. doi: 10.1007/s00401-023-02538-4. PMID: 36437415; PMCID: PMC9807491.

Keshwara SM, Gillespie CS, Mustafa MA, George AM, Richardson GE, Clynch AL Wang JZ, Lawson DDA, Gilkes CE, Farah JO, Yousaf J, Chavredakis E, Mills SJ Brodbelt AR, Zadeh G, Millward CP, Islim AI, Jenkinson MD. Quality of life outcomes in incidental and operated meningiomas (QUALMS): a cross-sectional cohort study. J Neurooncol. 2023 Jan;161(2):317- 327. 

Kumar S, Islim AI, Moon R, Millward CP, Hennigan D, Thorpe A, Foster M Pizer B, Mallucci CL, Jenkinson MD. Long term quality of life outcomes following surgical resection alone for benign paediatric intracranial tumours. J.Neurooncol. 2023 Jan;161(1):77-84. 

Lim YC, Jensen KE, Aguilar-Morante D, Vardouli L, Vitting-Seerup K, Gimple RC, Wu Q, Pedersen H, Elbaek KJ, Gromova I, Ihnatko R, Kristensen BW, Petersen JK, Skjoth-Rasmussen J, Flavahan W, Rich JN, Hamerlik P. Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy. Neuro Oncol. 2023 Feb 14;25(2):248-260. doi: 10.1093/neuonc/noac135. PMID: 35608632; PMCID: PMC9925708.

Loan JJM, Bacon A, van Beijnum J, Bhatt P, Bjornson A, Broomes N, Bullen A, Bulters D, Cahill J, Chavredakis E, Colombo F, Danciut M, Digpal R, Edwards RJ, Ferguson L, Forsyth L, Fouyas I, Ganesan V, Grover P, Gurusinghe N, Hall PS, Harkness K, Harris LS, Hayton T, Helmy A, Holsgrove D, Hutchinson PJ, Israni A, Kinsella E, Lewis S, Majeed S, Mallucci C, Mukerji N, Nair R, Neilson AR, Papadopoulos MC, Radatz M, Rossdeutsch A, Raza-Knight S, Stephen J, Stoddart A, Teo M, Turner C, Wade J, Walsh D, White D, White P, Wildman J, Wroe Wright O, Uff C, Ushewokunze S, Vindlacheruvu R, Kitchen N, Al-Shahi Salman R; Cavernomas A Randomised Effectiveness (CARE) pilot trial collaborators. Feasibility of comparing medical management and surgery (with neurosurgery or stereotactic radiosurgery) with medical management alone in people with symptomatic brain cavernoma - protocol for the Cavernomas: A Randomised Effectiveness (CARE) pilot trial. BMJ Open. 2023 Aug 9;13(8):e075187. doi: 10.1136/bmjopen-2023-075187. PMID: 37558454; PMCID: PMC10414059.

Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed W, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, Cazacu S, deCarvalho AC, Khasraw M, Kocakavuk E, Kouwenhoven MCM, Migliozzi S, Niclou SP, Niers JM, Ormond DR, Paek SH, Reifenberger G, Sillevis Smitt PA, Smits M, Stead LF, van den Bent MJ, Van Meir EG, Walenkamp A, Weiss T, Weller M, Westerman BA, Ylstra B, Wesseling P, Lasorella A, French PJ, Poisson LM; Consortium The GLASS; Verhaak RGW, Iavarone A, Noushmehr H. The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen. Cancer Res. 2024 Mar 4;84(5):741-756. doi: 10.1158/0008-5472.CAN-23-2093. PMID: 38117484; PMCID: PMC10911804.

Manfield J, Waqar M, Mercer D, Ehsan S, Bambrough J, Ibrahim N, Sivarajan K, Bailey M, Karabatsou K, Coope D, Ponnusamy A, Phang I, D'Urso PI. Multimodal mapping and monitoring is beneficial during awake craniotomy for intra-cranial tumours: results of a dual centre retrospective study. Br J Neurosurg. 2023 Apr;37(2):182-187. 

Millward CP, Keshwara S, Islim AI, Zakaria R, Jenkinson MD. Clinical Presentation and Prognosis. Adv Exp Med Biol. 2023; 1416:5-20. 

Mustafa MA, Richardson GE, Gillespie CS, Clynch AL, Keshwara SM, Gupta S George AM, Islim AI, Brodbelt AR, Duncan C, McMahon CJ, Sinha A, Jenkinson MD, Millward CP. Health-related quality of life following cranioplasty – a systematic review. Br J Neurosurg. 2023 Jun 2:1-11. 

Poon MTC, Piper RJ, Thango N, Fountain DM, Marcus HJ, Lippa L, Servadei F, Esene IN, Freyschlag CF, Neville IS, Rosseau G, Schaller K, Demetriades AK, Robertson FC, Hutchinson PJ, Price SJ, Baticulon RE, Glasbey JC, Bhangu A, Jenkinson MD, Kolias AG; Writing Group of the COVIDSurg-Cancer neurosurgery investigators on behalf of the COVIDSurg Collaborative; British Neurosurgical Trainee Research Collaborative; WFNS Young Neurosurgeons Committee; NIHR Global Health Research Group on Acquired Brain and Spine Injury. Variation in postoperative outcomes of patients with intracranial tumors: insights from a prospective international cohort study during the COVID-19 pandemic. Neuro Oncol. 2023 Jul 6;25(7):1299-1309. doi: 10.1093/neuonc/noad019. Erratum in: Neuro Oncol. 2023 Sep 5;25(9):1729. doi: 10.1093/neuonc/noad120. PMID: 37052643; PMCID: PMC10326494.

Suppree JS, Patel A, Keshwara SM, Krishna ST, Gillespie CS, Richardson GE Mustafa MA, Hart S, Islim AI, Jenkinson MD, Millward CP. Assessing the reporting quality of adult neuro-oncology protocols, abstracts, and trials: Adherence to the SPIRIT and CONSORT statements. Neurooncol Pract. 2023 Mar 22;10(4):391-401. 

Tew BY, Kalfa AJ, Yang Z, Hurth KM, Simon T, Abnoosian E, Durant ST, Hamerlik P, Salhia B. ATM-Inhibitor AZD1390 Is a Radiosensitizer for Breast Cancer CNS Metastasis. Clin Cancer Res. 2023 Nov 1;29(21):4492-4503. 

Theakstone AG, Brennan PM, Jenkinson MD, Goodacre R, Baker MJ. Investigating centrifugal filtration of serum-based FTIR spectroscopy for the stratification of brain tumours. PLoS One. 2023 Feb 17;18(2):e0279669. 

Villa C, Baussart B, Assié G, Raverot G, Roncaroli F. The World Health Organization classifications of pituitary neuroendocrine tumours: a clinico-pathological appraisal. Endocr Relat Cancer. 2023 Jun 22;30(8):e230021. 

Waqar M, Roncaroli F, Djoukhadar I, Akkari L, O'Leary C, Hewii L, Forte G, Jackson R, Hessen E, Withington L, Beasley W, Richardson J, Golby C, Whitehurst P, Colaco R, Bailey M, Karabatsou K, D'Urso PI, McBain C, Coope DJ, Borst GR. Study protocol: PreOperative Brain Irradiation in Glioblastoma (POBIG) - A phase I trial. Clin Transl Radiat Oncol. 2023 Jan 18;39:100585. 

Watts C, Dayimu A, Matys T, Ashkan K, Price S, Jenkinson MD, Doughton G, Mather C, Young G, Qian W, Kurian KM. Refining the Intraoperative Identification of Suspected High-Grade Glioma Using a Surgical Fluorescence Biomarker: GALA BIDD Study Report. J Pers Med. 2023 Mar 13;13(3):514. doi: 10.3390/jpm13030514. PMID: 36983696; PMCID: PMC10058333.

Weller M, Le Rhun E, Van den Bent M, Chang SM, Cloughesy TF, Goldbrunner R, Hong YK, Jalali R, Jenkinson MD, Minniti G, Nagane M, Razis E, Roth P, Rudà R, Tabatabai G, Wen PY, Short SC, Preusser M. Diagnosis and management of complications from the treatment of primary central nervous system tumors in adults. Neuro Oncol. 2023 Jul 6;25(7):1200-1224. doi: 10.1093/neuonc/noad038. PMID: 36843451; PMCID: PMC10326495.

Zakaria R, Jenkinson MD, Radon M, Das K, Poptani H, Rathi N, Rudland PS. Immune checkpoint inhibitor treatment of brain metastasis associated with a less invasive growth pattern, higher T-cell infiltration and raised tumor ADC on diffusion weighted MRI. Cancer Immunol Immunother. 2023 Oct;72(10):3387-3393. 

Zwain T, Alder JE, Zwayen S, Shaw A, Burrow AJ, Singh KK. Overcoming biological barriers BBB/BBTB by designing PUFA functionalised lipid-based nanocarriers for glioblastoma targeted therapy. Biomater Adv. 2023 Dec;155:213660. doi: 10.1016/j.bioadv.2023.213660. Epub 2023 Oct 11. PMID: 37976832.

2022

Aguilar-Morante D, Gómez-Cabello D, Quek H, Liu T, Hamerlik P, Lim YC. Therapeutic Opportunities of Disrupting Genome Integrity in Adult Diffuse Glioma. Biomedicines. 2022 Jan 31;10(2):332. 

Barrow R, Wilkinson JN, He Y, Callaghan M, Brüning-Richardson A, Dunning M, Stead LF. SpheroidAnalyseR-an online platform for analyzing data from 3D spheroids or organoids grown in 96-well plates. J Biol Methods. 2022 Nov 23;9(4):e163. 

Bor G, Salentinig S, Şahin E, Nur Ödevci B, Roursgaard M, Liccardo L, Hamerlik P, Moghimi SM, Yaghmur A. Cell medium-dependent dynamic modulation of size and structural transformations of binary phospholipid/ω-3 fatty acid liquid crystalline nano-self-assemblies: Implications in interpretation of cell uptake studies. J Colloid Interface Sci. 2022 Jan 15;606(Pt 1):464-479. 

Cameron JM, Brennan PM, Antoniou G, Butler HJ, ChrisUe L, Conn JJA, Curran.T, Gray E, Hegarty MG, Jenkinson MD, Orringer D, Palmer DS, Sala A, Smith BR Baker MJ. Clinical validation of a spectroscopic liquid biopsy for earlier detection of brain cancer. Neurooncol Adv. 2022 Feb 22;4(1). 

Cappoli N, Jenkinson MD, Dello Russo C, Dickens D. LAT1, a novel pharmacological target for the treatment of glioblastoma. Biochem Pharmacol. 2022 Jul;201:115103. 

Chari A, Piper RJ, Edlmann E, Woodfield J, Brennan PM, Turner C, Jenkinson.MD, Hutchinson PJ, Kolias AG; British Neurosurgical Trainee Research Collaborative. Delivering Large-Scale Neurosurgical Studies in the UK: The Impact of Trainees. World Neurosurg. 2022 May;161:343-349. 

Cheng VWT, de Pennington N, Zakaria R, Larkin JR, Serres S, Sarkar M, Kirkman.MA, Bristow C, Croal P, Plaha P, Campo L, Chappell MA, Lord S, Jenkinson MD Middleton MR, Sibson NR. VCAM-1-targeted MRI Improves Detection of the Tumor-brain Interface. Clin Cancer Res. 2022 Jun 1;28(11):2385-2396. 

Cousins O, Hodges A, Schubert J, Veronese M, Turkheimer F, Miyan J, Engelhardt B, Roncaroli F. The blood-CSF-brain route of neurological disease: The indirect pathway into the brain. Neuropathol Appl Neurobiol. 2022 Jun;48(4):e12789. 

Didikoglu A, Nair N, Robinson AC, Roncaroli F, Pendleton N, Payton A, Canal MM. The effect of season of birth on brain epigenome-wide DNA methylation of older adults. J Dev Orig Health Dis. 2022 Jun;13(3):367-377. 

Donofrio CA, Roncaroli F, Riccio L, Pereira M, O'Sullivan J, Mayers H, Poier GM, Djoukhadar I, Rutherford SA. A challenging case of sporadic melanocytoma of the jugular foramen. Neurochirurgie. 2022 Jul;68(4):453-457. 

George AM, Gupta S, Keshwara SM, Mustafa MA, Gillespie CS, Richardson GE Steele AC, Zamanipoor Najafabadi AH, Dirven L, Marson AG, Islim AI, Jenkinson.MD, Millward CP. Meningioma systematic reviews and meta-analyses: an assessment of reporting and methodological quality. Br J Neurosurg. 2022 Dec;36(6):678-685. 

Giannoudis A, Varešlija D, Sharma V, Zakaria R, Plai-Higgins A, Rudland PS Jenkinson MD, Young LS, Palmieri C. Characterisation of the immune microenvironment of primary breast cancer and brain metastasis reveals depleted T-cell response associated to ARG2 expression. ESMO Open. 2022 Dec;7(6):100636. 

Gillespie CS, Bligh ER, Poon MTC, Solomou G, Islim AI, Mustafa MA, Rominiyi.O, Williams ST, Kalra N, Mathew RK, Booth TC, Thompson G, Brennan PM, Jenkinson.MD; INTERVAL-GB Collaborative; British Neurosurgical Trainee Research. Collaborative (BNTRC); Neurology and Neurosurgery Interest Group (NANSIG) Neurology and Neurosurgery Interest Group. Imaging timing after glioblastoma surgery (INTERVAL-GB): protocol for a UK and Ireland, multicentre retrospective cohort study. BMJ Open. 2022 Sep 13. 

Gillespie CS, Richardson GE, Mustafa MA, Evans D, George AM, Islim AI Mallucci C, Jenkinson MD, McMahon CJ. How should we treat long-standing overt ventriculomegaly in adults (LOVA)? A retrospective cohort study. Neurosurg Rev..2022 Oct;45(5):3193-3200. 

Henderson D, Zafar A, Bjornson A, Razak A, Achawal S, Danciut M, Smith A, O'Reilly G, Rajaraman C, Bahl A. Prognostic factors following resection of intracranial metastases. Surg Neurol Int. 2022 May 27;13:219. 

Islim AI, Mantziaris G, Pikis S, Chen CJ, Bunevicius A, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad RM, Delabar V, Mathieu D, Lee CC, Yang HC, Liscak R, May J, Alvarez RM, Moreno NM, Tripathi M, Kondziolka D, Speckter H, Albert C, Bowden GN, Benveniste RJ, Lunsford LD, Sheehan JP, Jenkinson MD. Comparison of Active Surveillance to Stereotactic Radiosurgery for the Management of Patients with an Incidental Frontobasal Meningioma-A Sub-Analysis of the IMPASSE Study. Cancers (Basel). 2022 Mar.3;14(5):1300. 

Islim AI, Millward CP, Piper RJ, Fountain DM, Mehta S, Kolamunnage-Dona R, Ali U, Koszdin SD, Georgious T, Mills SJ, Brodbelt AR, Mathew RK, Santarius T Jenkinson MD; IMPACT Study Investigators, International Consortium on Meningioma. (ICOM) and British Neurosurgical Trainee Research Collaborative (BNTRC). External validation and recalibration of an incidental meningioma prognostic model - IMPACT: protocol for an international multicentre retrospective cohort study. BMJ Open. 2022 Jan 18;12(1): e052705. 

Karabid NM, Wiedemann T, Gulde S, Mohr H, Segaran RC, Geppert J, Rohm M, Vitale G, Gaudenzi G, Dicitore A, Ankerst DP, Chen Y, Braren R, Kaissis G, Schilling F, Schillmaier M, Eisenhofer G, Herzig S, Roncaroli F, Honegger JB, Pellegata NS. Angpt2/Tie2 autostimulatory loop controls tumorigenesis. EMBO Mol Med. 2022 May 9;14(5):e14364. 

Leahy CB, Robinson AC, Jabbari E, Morris HR, Lally I, Djoukhadar I, Roncaroli F, Kobylecki C. A case of Lewy body disease and anaplastic astrocytoma presenting with atypical parkinsonism. Neuropathology. 2022 Dec;42(6):540-547. 

Lewis D, Roncaroli F, Kearney T, Coope DJ, Gnanalingham K. Quantitative Magnetic Resonance-Derived Biomarkers as Predictors of Function and Histotype in Adenohypophyseal Tumours. Neuroendocrinology. 2022;112(3):276-286. 

Lilo T, Morais CLM, Ashton KM, Davis C, Dawson TP, Martin FL, Alder J, Roberts G, Ray A, Gurusinghe N. Raman hyperspectral imaging coupled to three-dimensional discriminant analysis: Classification of meningiomas brain tumour grades. Spectrochim Acta A Mol Biomol Spectrosc. 2022 May 15;273:121018. 

Loughrey PB, Roncaroli F, Healy E, Weir P, Baseb M, Casey RT, Hunter SJ, Korbonits M. Succinate dehydrogenase and MYC-associated factor X mutations in pituitary neuroendocrinetumours. EndocrRelatCancer.2022Sep2;29(10):R157-R172. 

Mantziaris G, Pikis S, Samanci Y, Peker S, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad RM, Delabar V, Mathieu D, Lee CC, Yang HC, Liscak R, Hanuska J, Alvarez RM, Moreno NM, Tripathi M, Speckter H, Albert C, Benveniste RJ, Bowden GN, Patel DN, Kondziolka D, Bernstein K, Lunsford LD, Jenkinson MD, Islim AI, Sheehan J. Stereotactic radiosurgery versus active surveillance for asymptomatic, skull-based meningiomas: an international multicenter matched cohort study. J Neurooncol. 2022 Feb;156(3):509-518. 

Millward CP, Armstrong TS, Barrington H, Bell S, Brodbelt AR, Bulbeck H CroÉon A, Dirven L, Georgious T, Grundy PL, Islim AI, Javadpour M, Keshwara SM Koszdin SD, Marson AG, McDermoi MW, Meling TR, Oliver K, Plaha P, Preusser M Santarius T, Srikandarajah N, Taphoorn MJB, Turner C, Wais C, Weller M Williamson PR, Zadeh G, Zamanipoor Najafabadi AH, Jenkinson MD; EORTC BTG, ICOM EANO, SNO, RANO-PRO, BNOS, SBNS, BIMS, TBTC, International Brain Tumour Alliance, Brainstrust, and Brain Tumour Foundation of Canada. Development of 'Core Outcome Sets' for Meningioma in Clinical Studies (The COSMIC Project): protocol for two systematic literature reviews, eDelphi surveys and online consensus meetings. BMJ Open. 2022 May 9;12(5):e057384. 

Millward CP, Armstrong TS, Barrington H, Brodbelt AR, Bulbeck H, Byrne A Dirven L, Gamble C, Grundy PL, Islim AI, Javadpour M, Keshwara SM, Krishna ST Mallucci CL, Marson AG, McDermoi MW, Meling TR, Oliver K, Pizer B, Plaha P Preusser M, Santarius T, Srikandarajah N, Taphoorn MJB, Wais C, Weller M Williamson PR, Zadeh G, Zamanipoor Najafabadi AH, Jenkinson MD. Opportunities and challenges for the development of "core outcome sets" in neuro-oncology. Neuro Oncol. 2022 Jul 1;24(7):1048-1055. 

Millward CP, Doherty JA, Mustafa MA, Humphries TJ, Islim AI, Richardson GE Clynch AL, Gillespie CS, Keshwara SM, Kolamunnage-Dona R, Brodbelt AR, Jenkinson.MD, Duncan C, Sinha A, McMahon CJ. Cranioplasty with hydroxyapatite or acrylic is associated with a reduced risk of all-cause and infection-associated explantation. Br J Neurosurg. 2022 Jun;36(3):385-393. 

Millward CP, Keshwara SM, Islim AI, Jenkinson MD, Alalade AF, Gilkes CE. Development and Growth of Intracranial Meningiomas in Transgender Women Taking Cyproterone Acetate as Gender-Affirming Progestogen Therapy: A Systematic Review. Transgend. Health. 2022 Nov 29;7(6):473-483. 

Nassiri F, Wang JZ, Au K, Barnholtz-Sloan J, Jenkinson MD, Drummond K, Zhou. Y, Snyder JM, Brastianos P, Santarius T, Suppiah S, Poisson L, Gaillard F, Rosenthal M, Kaufmann T, Tsang DS, Aldape K, Zadeh G. Consensus core clinical data elements for meningiomas (v2021.1). Neuro Oncol. 2022 May 4;24(5):683-693. 

Olubajo F, Thorpe A, Davis C, Sinha R, CroÉon A, Mills SJ, Williams M Jenkinson MD, Price SJ, Wais C, Brodbelt AR. Tumour treating fields in glioblastoma: is the treatment tolerable, effective, and practical in UK patients? Br J Neurosurg. 2022 Dec;36(6):770-776. 

Pangeni RP, Olivaries I, Huen D, Buzaio VC, Dawson TP, Ashton KM, Davis C, Brodbelt AR, Jenkinson MD, Bièche I, Yang L, Latif F, Darling JL, Warr TJ Morris MR. Genome-wide methylation analyses identifies Non-coding RNA genes dysregulated in breast tumours that metastasise to the brain. Sci Rep. 2022 Jan.20;12(1):1102. 

Park JJ, Ooi SZY, Gillespie CS, Bandyopadhyay S, Chowdhury YA, Solomou G Gough M, Kanmounye US, Yanez Touzet A, Poon MTC, Demetriades AK, Jenkinson MD Jenkins A; Neurology and Neurosurgery Interest Group (NANSIG). The Neurology and Neurosurgery Interest Group (NANSIG)-ten years of cultivating interest in clinical neurosciences. Acta Neurochir (Wien). 2022 Apr;164(4):937-946. 

Pauzaite T, Tollii J, Sopaci B, Caprani L, Iwanowytsch O, Thacker U, Hardy JG, Allinson SL, Copeland NA. Dbf4-Cdc7 (DDK) Inhibitor PHA-767491 Displays Potent Anti-Proliferative Effects via Crosstalk with the CDK2-RB-E2F Pathway. Biomedicines. 2022 Aug 19;10(8):2012.

Pikis S, Mantziaris G, Bunevicius A, Islim AI, Peker S, Samanci Y, Nabeel.AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad RM, Delabar V Mathieu D, Lee CC, Yang HC, Liscak R, May J, Alvarez RM, Patel DN, Kondziolka D Bernstein K, Moreno NM, Tripathi M, Speckter H, Albert C, Bowden GN, Benveniste RJ, Lunsford LD, Jenkinson MD, Sheehan J. Stereotactic Radiosurgery Compared With Active Surveillance for Asymptomatic, Parafalcine, and Parasagital Meningiomas: A Matched Cohort Analysis From the IMPASSE Study. Neurosurgery 2022 Jun 1;90(6):750-757. 

Plaha P, Camp S, Cook J, McCulloch P, Voets N, Ma R, Taphoorn MJB, Dirven L Grech-Sollars M, Wais C, Bulbeck H, Jenkinson MD, Williams M, Lim A, Dixon L Price SJ, Ashkan K, Apostolopoulos V, Barber VS, Taylor A; FUTURE-GB collaborators; Nandi D. FUTURE-GB: functional and ultrasound-guided resection of glioblastoma - a two-stage randomised control trial. BMJ Open. 2022 Nov.15;12(11):e064823. 

Pritchard AB, Fabian Z, Lawrence CL, Morton G, Crean S, Alder JE. An Investigation into the Effects of Outer Membrane Vesicles and Lipopolysaccharide of Porphyromonas gingivalis on Blood-Brain Barrier Integrity, Permeability, and Disruption of Scaffolding Proteins in a Human in vitro Model. J Alzheimers Dis. 2022;86(1):343-364. 

Quah BL, Edwards-Bailey A, Gnanalingham K, Pathmanaban O, Vasilopoulos H, Roncaroli F, Kearney T, Balogun J, Karabatsou K. Endoscopic transsphenoidal surgery for biochemically and clinically non-functioning adenohypophyseal tumours in the elderly: experience from a single UK centre. Endocrine. 2022 Mar;75(3):872-882. 

Schou Nørøxe, D., Flynn, A., Westmose Yde, C., Østrup, O., Cilius Nielsen, F., Skjøth-Rasmussen, J., Brennum, J., Hamerlik, P., Weischenfeldt, J., Skovgaard Poulsen, H., & Lassen, U. (2022). Tumor mutational burden and purity adjustment before and after treatment with temozolomide in 27 paired samples of glioblastoma: a prospective study. Molecular oncology, 16(1), 206–218. 

Islim AI, Mantziaris G, Pikis S, Chen CJ, Bunevicius A, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad RM, Delabar V, Mathieu D, Lee CC, Yang HC, Liscak R, May J, Alvarez RM, Moreno NM, Tripathi M, Kondziolka D, Speckter H, Albert C, Bowden GN, Benveniste RJ, Lunsford LD, Sheehan JP, Jenkinson MD. Comparison of Active Surveillance to Stereotactic Radiosurgery for the Management of Patients with an Incidental Frontobasal Meningioma-A Sub-Analysis of the IMPASSE Study. Cancers (Basel). 2022 Mar 3;14(5):1300. doi: 10.3390/cancers14051300. PMID: 35267608; PMCID: PMC8909178.

Solomou G, Gharooni AA, Patel W, Gillespie CS, Gough M, Venkatesh A, Poon MTC, Wykes V, Price SJ, Jenkinson MD, Watts C, Plaha P. Utility of 5-ALA for resection of CNS tumours other than high-grade gliomas: a protocol for a systematic review. BMJ Open. 2022 Jul 22;12(7):e056059. doi: 10.1136/bmjopen-2021-056059. PMID: 35868820; PMCID: PMC9315896.

Stead LF. Treating glioblastoma often makes a MES. Nat Cancer. 2022 Dec;3(12):1446-1448. 

Theakstone AG, Brennan PM, Ashton K, Czeiter E, Jenkinson MD, Syed K, Reed. MJ, Baker MJ; CENTER-TBI Participants and Investigators. Vibrational Spectroscopy for the Triage of Traumatic Brain Injury Computed Tomography Priority and Hospital Admissions. J Neurotrauma. 2022 Jun;39(11-12):773-783. 

Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D'Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW; GLASS Consortium. Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell. 2022 Jun 9;185(12):2184-2199.e16. 

Wang YY, Waqar M, Abou-Zeid A, Kearney T, Caputo C, Davis J, Trainer P, Higham C, Roncaroli F, Gnanalingham KK. Value of Early Post-Operative Growth Hormone Testing in Predicting Long-Term Remission and Residual Disease after Transsphenoidal Surgery for Acromegaly. Neuroendocrinology. 2022;112(4):345-357. doi: 10.1159/000517476. Epub 2021 May 28. PMID: 34052822.

Waqar M, Roncaroli F, Lehrer EJ, Palmer JD, Villanueva-Meyer J, Braunstein S, Hall E, Aznar M, De Witt Hamer PC, D'Urso PI, Trifiletti D, Quiñones-Hinojosa A, Wesseling P, Borst GR. Rapid early progression (REP) of glioblastoma is an independent negative prognostic factor: Results from a systematic review and meta-analysis. Neurooncol Adv. 2022 Jun 4;4(1):vdac075. doi: 10.1093/noajnl/vdac075. Erratum in: Neurooncol Adv. 2022 Aug 09;4(1):vdac125. doi: 10.1093/noajnl/vdac125. PMID: 35769410; PMCID: PMC9234755.

Archived publications from 1979 to 2021

Link for pdf download: Archived publications 1979-2021