Publications

on .

 

2017
Preliminary SAR on indole-3-carbinol and related fragments reveals a novel anticancer lead compound against resistant glioblastoma cells: Christopher Sherer, Ibrahim Tolaymat, Farzana Rowther, Tracy Warr, Timothy J. Snape*, Bioorg. Med. Chem. Lett., 2017, 27, 7, 1561-1565.

2016
Feature driven classification of Raman spectra for real-time spectral brain tumour diagnosis using sound. Stables, R., Clemens, G., Butler, H. J., Ashton, K. M., Brodbelt, A., Dawson, T. P., ... Baker, M. J. (2016). The Analyst. http://doi.org/10.1039/C6AN01583B

A review of novel analytical diagnostics for liquid biopsies: spectroscopic and spectrometric serum profiling of primary and secondary brain tumors.Spalding, K., Board, R., Dawson, T., Jenkinson, M. D., & Baker, M. J. (2016). Brain and Behavior, 502, e00502. http://doi.org/10.1002/brb3.502

Disruption of tumour-host communications by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth.
Soto MS, O'Brien ER, Andreau K, Scrace SF, Zakaria R., Jenkinson MD, O, Neill E., Sibson NR. Oncotarget: doi: 10.18632/oncotarget.10737.

Surgical management of posterior fossa metastases.
Sunderland G, Jenkinson MD, Zakaria R.
Journal of Neuro-Oncology (accepted):

Epilepsy and adverse quality of life in surgically resected meningioma.
Tanti M, Marson AP, Jenkinson MD.
Acta Neurological Scandinavica (accepted):

Incidental pineal cysts: is surveillance necessary?
Nevins EJ, Das K., Bhojak M, Pinto RS, Hoque M, Jenkinson MD, Chavredakis E.
World Neurosurgery 90: 96-102

Cell cycle progression in glioblastoma cells is unaffected by pathophysiological levels of hypoxia.
Richards R, Jenkinson MD, Haylock BJ, See V.
Peer J 3:4:e1755.doi:10.7717/peerj.

Early adjuvant radiotherapy in the treatment of atypical meningioma.
Jenkinson MD, Waqar M, Osman Farah J, Farrell M, Barbagallo GMV, McManus R, Looby S, Hussey D, Fitzpatrick D, Certo F, Javadpour M.
Journal of Clinical Neuroscience 2016 28:87-92.

EANO Guidelines for Management and Treatment of Meningiomas.
Goldbrunner R, Minniti G, Preusser M, Jenkinson MD, Sallabanda K, Houdart E, von Deimling A7, Stavrinou P, Lefranc F, Lund-Johansen M, Cohen E, Moyal J, Brandsma D, Henriksson R, Soffietti R, Weller M.
Lancet Oncology (in press):

Atypical meningioma – is it time to standardize surgical sampling technique?
Jenkinson MD, Santarius T, Alape K, Zadeh G.
Neuro-Oncology 2016 16(11): 1560-1561.

A quest towards personalized medicine for Grade II meningiomas – will need to zoom in.
Santarius T, Jenkinson MD, Kirollos RW.
Journal of Neuro-Oncology 2016 158(5): 931-932.

Incidental meningioma management – survey clinical practice of UK Neurosurgeons.
Jenkinson MD.
Society of Neuro-Oncology Conference on Meningioma, Toronto, Canada. 17-18 June 2016.

Seizure prophylaxis in meningioma surgery – are we practicing evidence-based medicine?
Jenkinson MD.
Society of Neuro-Oncology Conference on Meningioma, Toronto, Canada. 17-18 June 2016.

The impact of MGMT methylation and IDH-1 mutation on long-term outcome for glioblastoma treated with chemodiotherapy.
Millward CP, Brodbelt AR, Haylock B, Zakaria R, Baborie A, Crooks D, Husband D, Shenoy A, Wong H, Jenkinson MD, Acta Neurochir (Wien). 2016.

Combining random forest and 2D correlation analysis to identify serum spectral signatures for neuro-oncology. Smith BR, Ashton KM, Brodbelt A, Dawson T, Jenkinson MD, Hunt NT, Palmer DS, Baker MJ. Analyst. 2016 Jun 7;141(12):3668-78.

Metastais-inducing proteins are widely expressed in human brain metastases and associated with intracranial progression and radiation response. Zakaria R, Platt-Higgins A, Rathi N, Crooks D, Brodbelt A, Chavredakis E, Lawson D, Jenkinson MD, Rudland PS.Br J Cancer. 2016 May 10;114(10):1101-8.

Brain tumour differentiation: rapid stratified serum diagnostics via attenuated total reflection Fourier-transform infrared spectroscopy. Hands JR, Clemens G, Stables R, Ashton K, Brodbelt A, Davis C, Dawson TP, Jenkinson MD, Lea RW, Walker C, Baker MJ. J Neurooncol. 2016 May;127(3):463-72.

Introducting Discrete Frequency Infrared Technology for High-Throughput Biofluid Screening. Hughes C, Clemens G, Bird B, Dawson T, Ashton KM, Jenkinson MD, Brodbelt A, Weida M, Fotheringham E, Barre M, Rowlette J, Baker MJ. Sci Rep. 2016 Feb 4;6:20173.

WHO grade 1 meningioma recurrence: Are location and Simpson grade still relevant? Gallagher MJ, Jenkinson MD, Brodbelt AR, Mills SJ, Chavredakis E. Clin Neurol Neurosurg. 2016 Feb;141:117-21.

Anionic host defence peptides from the plant kingdom: their anticancer activity and mechanisms of action: Frederick Harris, Saurabh Prabhu, Sarah R. Dennison, Timothy J. Snape, Robert Lea, Manuela Mura and David A Phoenix, Protein & Peptide Letters, 2016, 23, In Press.

Brain Tumours Deserve More: Timothy J. Snape, Pan European Networks - Horizon 2020, 2016, In Press.

2015
Cyclic nucleotide phosphodiesterase-IC (PDE1C) drives cell proliferation, migration and invasion in glioblastoma multiforme cells in vitro. Molecular Carcinogenesis, (November), 1-12. doi:10.100/mc.22276.
Rowther, F.B., Wei, W., Dawson, T.P., Ashton, K., Singh, A., Madiesse-Timchou, M.P. Warr, T.

"Growth Hormone and Cancer: GH Production and action in Glioma?" General and Comparative Endocrinology 220 (September): 119-23. doi:10.1016/j.ygcen.2015.06.011.
Lea, Robert w, Timothy Dawson, Carlos G Martinez-Moreno, Nasra El-Abry and Steve Harvey.

Selective Targeting to Glioma with Nucleic Acid Aptamers. Plos One 10 (8): e0134957.doi:10.1371/journal.pone.0134957.
Aptekar, Shraddha, Mohit Arora, Clare Lousie Lawrence, Robert William Lea, Katherine Ashton, Tim Dawson, Jane Elizabeth Alder and Lisa Shaw.

The ROAM trial: Radiation versus Observation following surgical resection of Atypical Meningioma: a study protocol for a randomized controlled trial.
Jenkinson MD, Javadpour M, Haylock BJ, Young B, Gillard H, Vinten J, Bulbeck H, Das K, Farrell M, Looby S, Hickey H, Preusser M, Mallucci CL, Hughes D, Gamble C, Weber DC.
Trial 2015 16:519 DOl 10.1186/s13063-015-1040-3.

Linear accelerator radiosurgery for vestibular schwannoma: results of medium-term follow-up.
Ellenbogen, JR, Waqar, M, Kinshuck AJ, Jenkinson MD, Lesser TH, Husband D, Javadpour M.
British Journal of Neurosurgery 2015 12:1-7.

Genetics and Imaging of Oligodendroglial Tumours.
Ellenbogen JR, Walker C. Jenkinson MD.
CNS Oncology 4(5): 307-15

The impact of epilepsy on the quality of life of patients with epilepsy: a systematic review.
Tanti M, Marson AP, Jenkinson MD.
British Journal of Neurosurgery 2015 30(1): 23-8.

Atypical meningiomas: current clinical dilemmas and prospective clinical trials.
Jenkinson MD, Weber DC, Haylock BJ, Mallucci CL, Zakaria R, Javadpour M.
Journal of Neuro-Oncology 2015 121 (1): 1-7.

Paediatric intracranial anaplastic ependymoma: the role of multiple surgical resections for disease relapse in maintaining quality of life and prolonged survival.
Kitchen WJ, Pizer B, Pettorini B, Mallucci CL, Jenkinson MD.
Paediatric Neurosurgery 2015 50(2): 68-72.

Diffusion weighted MRI in a promising imaging biomarker in brain metastases.
Zakaria R, Jenkinson MD.
Journal of Neuro-Oncology 2015 121(2): 421-422.
World Federation of Neurosurgical Societies, Rome, Italy. 10 Sept 2015.

Prognostic Factors in Lobar World Health Organization Grade II Astrocytomas. Waqar M, Hanif S, Brodbelt AR, Rathi N, Das K, Zakaria R, Walker C, Jenkinson MD. World Neurosurg. 2015 Jul;84(1):154-62.

The 18-kDa mitochondrial translocator protein in human gliomas: an 11C-(R)PK11195 PET imaging and neuropathology study. Su Z, Roncaroli F, Durrenberger PF, Coope DJ, Karabatsou K, Hinz R, Thompson G, Turkheimer FE, Janczar K, Du Plessis D, Brodbelt A, Jackson A, Gerhard A, Herholz K. J Nucl Med. 2015 Apr;56(4):512-7

Glioblastoma in England: 2007-2011. Brodbelt A, Greenberg D, Winters T, Williams M, Vernon S, Collins VP; (UK) National Cancer Information Network Brain Tumour Group. Eur J Cancer. 2015 Mar;51(4):533-42.

The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain.
Pangeni RP, Channathodiyil P, Huen DS, Eagles LW, Johal BK, Pasha D, Hadjistephanou N, Nevell O, Davies CL, Adewumi AI, Khanom H, Samra IS, Buzatto VC, Chandrasekaran P, Shinawi T, Dawson TP, Ashton KM, Davis C, Brodbelt AR, Jenkinson MD, Bièche I, Latif F, Darling JL, Warr TJ, Morris MR. Clin Epigenetics. 2015 May 27;7:57.

The role of the corpus callosum in seizure spread: MRI lesion mapping in oligodendrogliomas. Wieshmann UC, Milinis K, Paniker J, Das K, Jenkinson MD, Brodbelt A, Crooks D, Keller SS. Epilepsy Res. 2015 Jan;109:126-33.

Approaches Towards Improving the Prognosis of Paediatric Glioma Patients: Pursuing Mutant Drug Targets with Emerging Small Molecules: Timothy J. Snape* and Tracy Warr, Seminars in Pediatric Neurology, 2015, 22, 28–34.

Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: exploring the scope of indole and carbazole derivatives: Chris Sherer and Timothy J. Snape,* Eur. J. Med. Chem., 2015, 97, 552-560.

2014
Application of Fourier transform infrared spectroscopy for analysis of biological materials towards understanding cell functionality, tissue imaging and disease diagnosis. Nature Protocols 9: 1771-1791:dio; 10.1038/nprot,2014,119 (Online 03 July 2014). Impact Factor:-7.782; featured on front of cover of journal issue.
Baker, M.J., Trevisan, J., Bassan, P., Bhargava, R., Butler, H.j., Dorling, K.M., Fielden, P.R., Fogarty, S.W., Fullwood, N.j., Heys, K.A., Hughes, C., Lasch, P.,Martin-Hirsch, P.L., Obinaju, B., Sockalingum, G.D., Sulé-Suso, J., Strong, R.J., Walsh, M.J., Wood, B.R., Gardner, P. and Martin, F.L..

Vibrational spectroscopy of biofluids for disease screening or diagnosis: translation from the laboratory to a clinical setting. Journal of Biophotonics 7: 153-165; doi: 10.1002/jbio.201400018 (Online 19 March 2014).
Mitchell, A.L., Gajjar, K.B., Theophiliou, G., Martin, F.L. and Martin-Hirsch, P.L.

Measuring similarity and improving stability in biomarker identification methods applied to Fourier-transform infrared (FTIR) spectroscopy. Journal of Biophotonics 7:254-265; doi: 10.1002/jbio.201300190 (07 March 2014).
Trevisan, J., Park, J., Angelov, P.P., Ahmadzai, A.A., Gajjar, K., Scott, A.D., Carmichael, P.L and Martin, F.L.

Diagnostic challenges, management and outcomes of midline low-grade gliomas.
Waqar, M, Hanif S, Rathi N, Das K, Zakaria R, Brodbelt AR, Walker C, Jenkinson MD.
Journal of Neuro-Oncology 2014 120(2): 389-398.

Diffusion-weighted MRI characteristics of the cerebral metastasis to brain boundary predicts
Patient outcomes.
Zakaria R, Das K, Radon M, Bhojak M, Rudland PR, Slumming V, Jenkinson MD.
BMC Medical Imagaing 2014 14(1): 26. Doi 10.1186/1471-2342-14-26.

Neurosurgery in Octogenarians.
Stovell MG, Jenkinson MD.
British Journal of Neurosurgery 2014 28(5): 611-615.

The reliability of routine clinical post-processing software I assessing potential diffusion weighted MRI "biomarkers" in brain metastases.
Zakaria R, Das K, Bhojak M, Radon M, Slumming V, Walker C, Jenkinson MD.
Magnetic Resonance Imaging 2014 32(3): 291-296.

Unusual patterns of recurrence in low grade gliomas.
Ellenbogen JR, Davies P, Eldridge PR, Jenkinson MD.
Journal of Clinical Neuroscience 2014 (21): 360-363.

The role of magnetic resonance imaging in the management of brain metastases: diagnosis to prognosis.
Zakaria R, Das K, Bhojak M, Radon M, Slumming V, Walker C, Jenkinson MD.
Cancer Imaging 2014 14(1): 8.

Low grade glioma in an adult patient with Sotos syndrome.
Theodoulou E, Barborie A, Jenkinson MD.

Radiotherapy versus Observation following surgical resection of Atypical Meningioma (the ROAM trial).
Jenkinson MD, Weber DC, Haylock BJ, Mallucci CL, Zakaria R, Javadpour M.
Neuro-Oncology 2014 16(11): 1560-1561.

Diagnostic challenges, management and outcomes of midline low-grade gliomas. Waqar M, Hanif S, Rathi N, Das K, Zakaria R, Brodbelt AR, Walker C, Jenkinson MD. J Neurooncol. 2014 Nov;120(2):389-98.

Indications for intracranial reservoirs: a six-year study. Srikandarajah N, Patel A, Lee MK, Brodbelt A. Br J Neurosurg. 2014 Aug;28(4):475-7.

Fourier Transform Infrared Spectroscopy: Biological Materials' Analyses Towards Understanding Cell Functionality. Tissue Imaging and Disease Diagnosis. Nature Protocols. Baker MJ, Trevisan J, Bassan P, Bhargava R, Butler H, Dorling KM, Fielden PR, Fogarty SJ, Fullwood NJ, Heys K, Hughes C, Lasch P, Martin-Hirsch PL, Obinaju B, Sockalingum GD, Sule-Suso J, Strong RJ, Walsh MJ, Wood BR, Gardner P & Martin FL, (2014)

Vibrational Spectroscopic Analysis of Body Fluids: Avoiding Molecular Contamination Using Centrifugal Filtration. Analytical Methods. Bonnier F, Baker MJ Byrne HJ, (2014)
Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity. Bioorg. Med. Chem. Lett. Fahs S, Rowther FB, Dennison SR, Patil-Sen Y, Warr T & Snape TJ, (2014)

Investigating the use of Raman and Immersion Raman Spectroscopy for Spectral Histopathology of Metastatic Brain Cancer and Primary Sites of Origin. Analytical Methods (Special Issue on Clinical Diagnostics) - DOI: 10.1039/C3AY42190B). Fullwood LM, Clemens G, Griffiths D, Ashton K, Dawson TP, Lea RW, Davis C, Bonnier F, Byrne HJ & Baker MJ, (2014)

Cn-AMP2 from green coconut water is an anionic anticancer peptide. Journal of Peptide Science. Prabhu S, Dennison SR, Mura M, Lea B, Snape T J & Harris, F (2014)

A review of small molecule clinical trial candidates for the treatment of glioma. Drug Discovery Today. Prabhu S, Harris F, Lea RW & Snape TJ, (2014)

Circulating MicroRNA Biomarkers for Glioma and Predicting Response to Therapy. Molecular Neurobiology. Tumilson CA, Lea RW, Alder JE & Shaw L, (2014)

The role of magnetic resonance imaging in the management of brain metastases: diagnosis to prognosis, Cancer Imaging. 2014 14(1): 8 Zakaria R, Das K, Bhojak M, Radon M, Slumming V, Walker C & Jenkinson MD

The reliability of routine clinical post-processing software in assessing potential diffusion weighted MRI "biomarkers" in brain metastases. Magnetic Resonance Imaging, 32(3):291-296. Zakaria R, Das K, Bhojak M, Radon M, Slumming V, Walker C & Jenkinson MD, (2014)

Photonic Biofluid Diagnostics. Journal of Biophotonics, 7(3-4): 151-152. Baker MJ, (2014)

Improved Protocols for Vibrational Spectroscopic Analysis of Bodily Fluids. Journal of Biophotonics, 7(3-4): 167-179. Bonnier F, Petitjean F, Baker MJ & Byrne HJ, (2014)

Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) Spectral Discrimination of Brain Tumour Severity from Serum Samples. Journal of Biophotonics, 7(3-4):189-199. Hands JR, Dorling KM, Abel P, Ashton KM, Brodbelt A, Davis C, Dawson T, Jenkinson MD, Lea RW, Walker C & Baker MJ, (2014)

Unusual patterns of recurrence in low grade gliomas. Journal of Clinical Neuroscience, 21:360-363. Ellenbogen JR, Davies P, Eldridge PR & Jenkinson MD, (2014)

Effect of Substrate Choice and Tissue Type on Tissue Preparation for Spectral Histopathology by Raman Microspectroscopy. Analyst, 139(2): 446-454. Fullwood LM, Griffiths D, Ashton K, Dawson TP, Lea RW, Davis C, Bonnier F, Byrne HJ & Baker MJ, (2014)

Could Upregulated Hsp70 Protein Compensate for the Hsp90-Silence-Induced Cell Death in Glioma Cells? International Journal of Brain Science, vol. 2014, Article ID 652643, 9 pages doi:10.1155/2014/652643. Munje C, Shervington L, Khan Z & Shervington A, (2014)

Revealing stem cells I the inter-follicular epidermis of human skin by IR microspectroscopy. Diamond Light Source Annual Review (Accepted).

Verma, V.K., Butler, H.j., Setty, S., Martin, F.L. and Walsh, M.J. (2014) Cover image. Nature Protocols, volume 9, issue no 8.

2013
Surgical pathway and management of pineal region tumours in children.
Pettorini BL, Al-Mahfoud R, Jenkinson MD, Avula S, Pizer B, Mallucci CL.
Childs Nervous System 2013 29(3): 533-439.

Intracranial granuloma mimicking a brain tumor in a patient with scleroderma.
Patel A, Rathi N, Lee MK, Baborie A, Jenkinson MD.

Image-guided stereotaqctic biopsy of pineal region tumour using CT venography in a patient with a pacemaker: a technical note.
Stovell MG, Jenkinson MD.
British Journal of Neurosurgery 2013 27(3): 398-400.

Establishing the efficacy of Gliadel wafers: progress towards a Phase III trial.
Watts C, Dunn L, Keyoumars A, Jenkinson MD, Smith P.
Acta Neurochir 2013 155: 61-62.

Prolonged survival associated with the use of intraoperative carmustine (Gliadel) in a paediatric patient with recurrent grade III astrocytoma. Pizer B, Salehzadeh A, Brodbelt A, Mallucci C. Br J Neurosurg. 2013 Aug;27(4):516-8.

Glioblastoma multiforme intraxial metastasis to the conus medullaris with primary disease under control: a rare unexpected finding. Sabatino G, Della Pepa GM, Esposito G, Brodbelt A. Br J Neurosurg. 2013 Jun;27(3):388-9.

Is stereotactic radiosurgery under-utilised in the management of cerebral metastases? British Journal of Neurosurgery 27(5):658-661. Lee MK, Javadpour M & Jenkinson MD, (2013)

Investigating the Rapid Diagnosis of Gliomas from Serum Samples using Infrared Spectroscopy and Cytokine and Angiogenesis Factors. Analytical and Bioanalytical Chemistry, 405(23): 7347-7355. Hands JR, Abel P, Ashton K, Dawson T, Davis C, Lea R, McIntosh AJS & Baker MJ (2013).

Rapid FTIR chemical imaging: highlighting FPA detectors. Trends In Biotechnology, 31(8): 437-438. Dorling K & Baker MJ, (2013)

The Complexity of Identifying Cancer Stem Cell Biomarkers. Cancer Investigation, 31(6):404-11. Khan Z, Shervington LA, Munje C & Shervington A, (2013)
Highlighting ATR-FTIR Spectroscopy for Rapid Serum Analysis. Trends In Biotechnology, 31(6): 327-328. Dorling K & Baker MJ, (2013)

Preliminary biological evaluation and mechanism of action studies of selected 2-arylindoles against glioblastoma. Bioorg. Med. Chem., 21: 1918-1924. Prabhu S, Akbar Z, Harris F, Karakoula K, Lea RW, Rowther F, Warr T & Snape TJ, (2013)

Anionic antimicrobial and anticancer peptides from plants Crit. Rev. Plant Sci., 32:303-320. Prabhu S, Dennison SR, Lea RW, Snape TJ, Nichol ID, Radek I & Harris F, (2013)

Surgical pathway and management of pineal region tumours in children Childs Nervous System 29(3):433-439.
Pettorini BL, Al-Mahfoud R, Jenkinson MD, Avula S, Pizer B & Mallucci CL, (2013)

2012
Outcome and prognostic features in adult pineoblastomas: analysis of cases from the SEER database.
Selvanathan SK, Hammouche S, Smehturst W, Salminen HJ, Jenkinson MD.
Acta Neurochir 2012 154(5): 863-869.

Patient centred management of cerebral metastases (Invited review).
Jenkinson MD, Haylock B.
RAD Magazine 2012.

Diagnostic segregation of human brain tumours using Fourier-transform infrared and/or Raman spectroscopy coupled with discriminant analysis Anal. Methods, Advance Article
Gajjar K, Heppenstall LD, Pang W, Ashton KM, Trevisan J, Patel II, Llabjani V, Stringfellow HF, Martin-Hirsch PL, Dawson T & Martin FL, (2012)

Is cd133 the appropriate stem cell marker for glioma? In: Stem Cells and Cancer Stem Cells, Therapeutic Applications in Disease and Injury: Volume 1 Series: Stem Cells and Cancer Stem Cells, Hayat, M.A. (Ed.) 1st Edition, XV, 198 p. 26 illus.,18 in colour. Hardcover, ISBN 978-94-007-1708-4
Khan Z, Shervington L & Shervington A, (2012)

Exploiting conformationally restricted N, N'-dimethyl-N,N'-diarylureas as biologically active C=C double bond analogues: synthesis and biological evaluation of combretastatin A-4 analogues. RSC Adv. 2:7557-7560.
Snape TJ, Karakoula K, Rowther F & Warr T, (2012)

The Complexity of Identifying Cancer Stem Cell Biomarkers. Cancer (Accepted) Impact Factor: 4.771
Khan Z, Shervington LA, Munje C & Shervington A, (2012)

Preliminary biological evaluation and mechanism of action studies of selected 2-arylindoles against glioblastoma: Bioorg. Med. Chem.
Prabhu S, Akbar Z, Harris F, Karakoula K, Lea R, Rowther F, Warr T & Snape, T (2012)

2011
Biospectroscopy to metabolically profile biomolecular struction: a multi-stage approach linking computational analysis with biomarkers. Journal of Proteome Research 10: 1437-1488; doi: 10.1021/pr101067u (Online 06 January 2011).
Kelly, J.g., Trevisan, J., Scott, A.D., Carmichael, P.L., Pollock, H.M., Martin-Hirsch, P.l. and Martin, F.L.

Classification of CNS tumours I and II in: ePub www.ebrainjnc.com Module 5, 2011.
Dawson T.P.

Recurrent spindle cell oncocytoma of the pituitary, a case report and review of literature. Pituitary. Dec;14(4):367-70.

Outcome and prognostic features in anaplastic ganglioglioma: analysis of cases from the SEER database.
Selvanathan SK, Hammouche S, Salminen HJ, Jenkinson MD.
Journal of Neuro-Oncology 2011 105(3): 539-545.

Biology, genetics and imaging of glial cell tumours.
Walker C, Baborie A, Crooks D, Wilkins S, Jenkinson MD.
British Journal of Radiology 2011 84:S90-S109.

Management of cerebral metastasis: evidence-based approach for surgery, stereotactic radiosurgery and radiotherapy.
Jenkinson MD, Haylock B, Shenoy A, Husband D, Javadpour M.
European Journal of Cancer 2011 47 (5): 649-655.

Clinical applications of imaging biomarkers Part 2. The neurosurgeon's perspective.
Brodbelt A, Br J Radiol. 2011 Dec:84 Spec No 2:S205-8.

Validating the Efficacy of shRNA vs. siRNA In Silencing Hsp90α in Gliomas. J Bioanal Biomed S3: 002.
Munje C, Shervington L, Mehta A, Khan Z, Shervington A (2011)

Cell Survival Assays For Individualised Chemotherapy In Primary Glioma Cultures – Colourmetric Or Luminescent? Neuroscience and Medicine 2(4); 376-383
Dawson TP, K Ashton, A Golash and C H G Davis,R V Iyer, R W Lea, P Roberts and F Harris (2011).

Novel actions of thyroid hormone on glioma tumour cells. J. Thyroid Research. 1-8. Impact Factor currently being computed.
Liappas A, Iordanis M, Zisakis A, Lea RW & Constantinos P, (2011).

Proteomic studies coupled with RNAi methodologies can shed further light on the downstream effects of telomerase in glioma, Cancer Investigation 29 113-122. Impact Factor 2.4
Thakkar D, Shervington LA & Shervington A, (2011)

A Novel Therapeutic Strategy for the Treatment of Glioma, Combining Chemical and Molecular Targeting of Hsp90a. Cancers 2011, 3, 4228-4244.
Mehta, A.; Shervington, L.; Munje, C.; Shervington, A.

2010
Distinguishing cell types of populations based on the computational analyses of their infrared spectra. Nature Protocols 5:1948-1760; doi: 10.1038/nprot.2010-133 (Online 07 October 2010)
Martin, F.L., Kelly, J.G., Llabjani, V., Martin-Hirsch, P.L., Patel, I.I., Trevisan J., Fullwood, N.J. and Walsh, J.J.

Phase II trial of intratumoural BCNU injection and radiotherapy untreated adult malignant glioma.
Jenkinson MD, Smith TS, Kopitzki K, Vinjamuri S, Walker C, Pietronigro D, Warnke PC.
Journal of Neuro-Oncology 2010 99 (1): 103-113.

Relationship between apparent diffusion coefficient and quantitative assessment of cellularity in oligodendroglial tumours characterized by genotype.
Jenkinson MD, du Plessis DG, Smith TS, Brodbelt AR, Joyce KA, Walker C.
Journal of Neuro-Oncology 2010 96 (3): 385-392.

PgP and MRP immunostaining in gliomas – does the expression of PgP and MRP correlate with chemosensitivity in glioma cell cultures? Neuropath and Appl Neurobiol. 36(Suppl 1); 43
Sutton CM, Ashton K, Dawson TP. (2010)

The MTS versus the ATP assay for in vitro chemosensitivity testing of primary glioma tumour culture Neuropath and Appl Neurobiol. 36; 564-7
Dawson TP, Iyer R V, Lea R W, Roberts P, Harris, F, Ashton K, Golash A, and Davis C H G (2010).

Can hsp90alpha targeted siRNA combined with tmz be a future therapy for glioma?. Cancer Invest. (2010) 28: pp. 608-614.
Cruickshanks N, Shervington L, Patel R, Munje C, Thakkar D & Shervington A.

Intraoperative Ultrasound in Neurosurgery - a Practical Guide.
M Ivanov, S Wilkins, I Poeata, A Brodbelt. (2010).
British Journal of Neurosurgery 24(5):510–517

Molecular genetics, imaging and treatment of oligodendroglial tumours. Acta Neurochirugica 152(11):1815-25
Jenkinson M.D. Walker C., Brodbelt A.R., Wilkins S., Husband, D and Haylock B. (2010)

Gene expression in oligodendroglial tumors. Analytical Cellular Pathology / Cellular Oncology. 33(2):81-94
Shaw E.J., Haylock B., Husband D., du Plessis D., Sibson D.R., Warnke P. C and Walker C. (2010)

Cellularity and apparent diffusion coefficient in oligodendroglial tumours characterized by genotype. J Neurooncol 96(3) 385-92.
Jenkinson, M. D., du Plessis, D. G., Smith, T. S., Brodbelt, A. R., Joyce, K. A., and Walker, C. (2010).

An Investigation of the RWPE Prostate Derived Family of Cell Lines Using FTIR Spectroscopy The Analyst. 135:887- 894. Impact Factor 4.230
Baker MJ, Clarke C, Demoulin D, Nicholson JM, Lyng FM, Byrne HJ, Hart CA, Brown M D, Clarke NW & Gardener P, (2010)

2009
Telomerase and DNA repair in glioma. Biochim. Biophys. Acta (2009) 1792: pp. 275-279.
Patel R & Shervington A.

The sensitization of glioma cells to cisplatin and tamoxifen by the use of catechin. Mol. Biol. Rep. (2009) 36: pp. 1181-1186.
Shervington A, Pawar V, Menon S, Thakkar D & Patel R.

Telomerase downregulation in cancer brain stem cell. Mol. Cell. Biochem. (2009) 331: pp. 153-159.
Shervington A, Lu C, Patel R & Shervington L.

Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy. Br J Cancer 101, 124-131.
Dunn, J., Baborie, A., Alam, F., Joyce, K., Moxham, M., Sibson, R., Crooks, D., Husband, D., Shenoy, A., Brodbelt, A., Wong, H., Liloglou, T., Haylock, B., and Walker, C. (2009).

Investigating FTIR Based Histopathology for the Diagnosis of Prostate Cancer. Journal of Biophotonics 2:104-113. Impact Factor: 4.343
Baker, MJ, Gazi E, Brown MD, Shanks JH, Clarke NW & Gardner P, (2009)

Analysis of interleukin (IL)-8 expression in human astrocytomas: associations with IL-6, cyclooxygenase-2, vascular endothelial growth factor and microvessel morphometry. Hum. Immunol. 70:391-397. Impact Factor: 2.872
Samaras V, Piperi C, Levidou G, Zisakis A, Kavantzas N, Themistocleus MS, Boviatsis EI, Barbatis C, Lea RW, Kalofoutis A & Korkolopoulou P. (2009).

To determine the cytotoxicity of chlorambucil and one of its nitro derivatives, conjugated to prasterone and pregrnenolone towards eight human cancer cell lines, European Journal of Medicinal Chemistry. 44: 2944-2951. Impact Factor: 3.356
Shervington, LA Smith N, Norman ET, Ward T, Phillips R & Shervington A, (2009)

2008
Can the lack of HSP90alpha protein in brain normal tissue and cell lines, rationalise it as a possible therapeutic target for gliomas? Cancer Invest. 2008 Nov;26(9):900-4.
Shervington A, Cruickshanks N, Lea R, Roberts G, Dawson T, Shervington L. (2008)

Old Drugs New Tricks? Gemcitabine sensitive gliomas. Clinical Neuropathology 27(3):215
Dawson TP, Abeygunaratne R, Roberts P, Lea RW, Ashton K, Davis CHG. (2008)

FTIR Based Spectroscopic Analysis on the Identification of Clinically Aggressive Prostate Cancer. British Journal of Cancer. 99:1859-1866. Impact Factor: 5.042
Baker MJ, Gazi E, Brown, MD, Shanks JH, Gardner P & Clarke NW, (2008)

Discrimination of Prostate Cancer Cells and Non-Malignant Cells using Secondary Ion Mass Spectrometry The Analyst. 133:175-179. Impact Factor: 4.230
Baker MJ, Brown, MD, Gazi E, Clarke NW, Vickerman JC, and Lockyer NP, (2008)

ToF-SIMS PC-DFA Analysis of Prostate Cancer Cell Lines Applied Surface Science. 255:1190-1192. Impact Factor: 2.103
Baker MJ, Gazi E, Brown MD, Clarke, NW, Vickerman, JC & Lockyer, NP, (2008)

Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma. Brain Research. 1188; 173-181. Impact Factor: 2.665
Patel R, Shervington LA, Lea R & Shervington A (2008)

2007
Outcome predictors in the management of spinal cord ependymoma.
Quigley DG, Farooqi N., Pigott TJD, Findlay GFG, Pillay R, Buxton N, Jenkinson MD.
European Spine Journal 2007 16(3): 399-404.

Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma. Brain Res. 23;1134(1):45-52.
Shervington A, Patel R, Lu C, Cruickshanks N, Lea R, Roberts G, Dawson T, Shervington L. (2007)

Advanced MRI in the management of adult gliomas. Br J Neurosurg 21, 550-561.
Jenkinson, M. D., Du Plessis, D. G., Walker, C., and Smith, T. S. (2007).

Apparent diffusion coefficients in oligodendroglial tumors characterized by genotype. J Magn Reson Imaging 26, 1405-1412.
Jenkinson, M. D., Smith, T. S., Brodbelt, A. R., Joyce, K. A., Warnke, P. C., and Walker, C. (2007).

Expression of cellular adhesion molecule 'OPCML' is down-regulated in gliomas and other brain tumours. Neuropathol Appl Neurobiol 33, 77-85.
Reed, J. E., Dunn, J. R., du Plessis, D. G., Shaw, E. J., Reeves, P., Gee, A. L., Warnke, P. C., Sellar, G. C., Moss, D. J., and Walker, C. (2007).

2006
Genetic and metabolic predictors of chemosensitivity in oligodendroglial neoplasms. Br J Cancer 95, 1424-1431.
Walker, C., Haylock, B., Husband, D., Joyce, K. A., Fildes, D., Jenkinson, M. D., Smith, T., Broome, J., Kopitzki, K., du Plessis, D. G., Prosser, J., Vinjamuri, S., and Warnke, P. C. (2006).

Cerebral blood volume, genotype and chemosensitivity in oligodendroglial tumours. Neuroradiology 48, 703-713.
Jenkinson, M. D., Smith, T. S., Joyce, K. A., Fildes, D., Broome, J., du Plessis, D. G., Haylock, B., Husband, D. J., Warnke, P. C., and Walker, C. (2006).

Clinical use of genotype to predict chemosensitivity in oligodendroglial tumors. Neurology 66, 1661-1667.
Walker, C., Haylock, B., Husband, D., Joyce, K. A., Fildes, D., Jenkinson, M. D., Smith, T., Broome, J., du Plessis, D. G., and Warnke, P. C. (2006).

Histological growth patterns and genotype in oligodendroglial tumours: correlation with MRI features. Brain 129, 1884-1891.
Jenkinson, M. D., du Plessis, D. G., Smith, T. S., Joyce, K. A., Warnke, P. C., and Walker, C. (2006).

Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours. Br J Cancer 94, 1186-1193.
Dunn, J. R., Reed, J. E., du Plessis, D. G., Shaw, E. J., Reeves, P., Gee, A. L., Warnke, P., and Walker, C. (2006).

A feasibility study of chemosensitivity testing in primary cultures from malignant gliomas, and analysis of drug resistance mechanisms MD thesis, University of Central Lancashire, Preston, UK.
Iyer RV (2006)

Glioma: what is the role of c-myc, hsp90 and telomerase?. Mol. Cell. Biochem. (2006) 283: pp. 1-9.
Shervington A, Cruickshanks N, Wright H, Atkinson-Dell R, Lea R, Roberts G &
Shervington L.

2000 - 2005
Walker, C., Joyce, K., Du Plessis, D., MacHell, Y., Sibson, D. R., and Broome, J. (2000). Molecular genetic analysis of archival gliomas using diagnostic smears. Neuropathol Appl Neurobiol 26, 441-447.

Andrews, N., Helliwell, T., Walker, C., and Jones, A. S. (2000). Differing expression of bax and bcl-3 may influence the different cure rates in mouth and orophayrngeal cancer. Clin Otolaryngol Allied Sci 25, 570-576.

Thompson-Hehir, J., Davies, M. P., Green, J. A., Halliwell, N., Joyce, K. A., Salisbury, J., Sibson, D. R., Vergote, I., and Walker, C. (2000). Novel polymerase chain reaction approach for full-coding p53 mutation detection in microdissected archival tumors. Diagn Mol Pathol 9, 110-119.

Walker, C., Joyce, K. A., Thompson-Hehir, J., Davies, M. P., Gibbs, F. E., Halliwell, N., Lloyd, B. H., Machell, Y., Roebuck, M. M., Salisbury, J., Sibson, D. R., Du Plessis, D., Broome, J., and Rossi, M. L. (2001). Characterisation of molecular alterations in microdissected archival gliomas. Acta Neuropathol 101, 321-333.

Walker, C., du Plessis, D. G., Joyce, K. A., Machell, Y., Thomson-Hehir, J., Al Haddad, S. A., Broome, J. C., and Warnke, P. C. (2003). Phenotype versus genotype in gliomas displaying inter- or intratumoral histological heterogeneity. Clin Cancer Res 9, 4841-4851.
du Plessis, D. G., Rutherfoord, G. S., Joyce, K. A., and Walker, C. (2004). Phenotypic and genotypic characterization of glioblastoma multiforme with epithelial differentiation and adenoid formations. Clin Neuropathol 23, 141-148.

Walker, C., du Plessis, D. G., Fildes, D., Haylock, B., Husband, D., Jenkinson, M. D., Joyce, K. A., Broome, J., Kopitski, K., Prosser, J., Smith, T., Vinjamuri, S., and Warnke, P. C. (2004). Correlation of molecular genetics with molecular and morphological imaging in gliomas with an oligodendroglial component. Clin Cancer Res 10, 7182-7191.

du Plessis, D. G., Rutherfoord, G. S., Joyce, K. A., and Walker, C. (2004). Phenotypic and genotypic characterization of glioblastoma multiforme with epithelial differentiation and adenoid formations. Clin Neuropathol 23, 141-148.

Jenkinson, M. D., Smith, T. S., Joyce, K., Fildes, D., du Plessis, D. G., Warnke, P. C., and Walker, C. (2005). MRS of oligodendroglial tumors: correlation with histopathology and genetic subtypes. Neurology 64, 2085-2089.

Walker, C., du Plessis, D. G., Joyce, K. A., Fildes, D., Gee, A., Haylock, B., Husband, D., Smith, T., Broome, J., and Warnke, P. C. (2005). Molecular pathology and clinical characteristics of oligodendroglial neoplasms. Ann Neurol 57, 855-865.

Pre-2000
Davies, M. P., Gibbs, F. E., Halliwell, N., Joyce, K. A., Roebuck, M. M., Rossi, M. L., Salisbury, J., Sibson, D. R., Tacconi, L., and Walker, C. (1999). Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas. Br J Cancer 79, 1542-1548.

Fossati, G., Ricevuti, G., Edwards, S. W., Walker, C., Dalton, A., and Rossi, M. L. (1999). Neutrophil infiltration into human gliomas. Acta Neuropathol 98, 349-354.